Peripheral Pulse Analyzer, a computer based system developed at Bhabha Atomic Research Centre, for the study of physiological variabilities. It has unique feature that it yields heart rate variability, respiration rate variability, cardiac output variability/ peripheral blood flow variability from a single data acquisition session from the patient. The picture shows Peripheral Pulse Analyzer system in operation developed at BARC. The data acquisition is controlled by the PC, serially connected to the acquisition unit. The variability analysis and transfer to database is performed by the PC with the help of Peripheral Pulse Analyzer package in post processing module.

SALIENT FEATURES

• User friendly.
• Easy & faster data entry and retrieval from Access/Excel Database.
• Easy adaptability by clinicians/ medical practitioners.
• Comparison facility of the data from the same disease group and with the normal group
• Analysis of the data in the validation phase, user defined reports/queries for comparison of variability of different disease groups.
• Pictorial representation in the form of graph for comparing changes (increase/decrease) in the parameters (peak amplitude) for all variability and for all disease can be obtained to view the whole data at a glance.
• Queries are being used for finding out number of patients, average and standard deviation of a particular disease group.
• Till the frequency ranges are established for LF1, LF2, MF1, MF2, HF1 and HF2, flexibility to set the frequency ranges so that peak can be shifted automatically.
• Future expandability to accommodate new fields, variables, reports or queries.
• Future support for employing fuzzy logic or neural network approach to incorporate automatic machine generated report on the patient.

APPLICATION AREAS

• Helpful in studying Physiological Variability.
• Helpful in Studying Autonomous Nervous System.
• Helpful in finding the effects of Allopathic/ Ayurvedic/ Homeopathic Medicines on the patients.

Variability is the sign of life; therefore higher variability in physiological parameters is generally an indicator of better health. The use of variability for the diagnosis of several diseases is age old. Because of great potential of this technique, heart rate variability monitoring is a routine feature in the patient monitoring systems available in the market for employment in intensive care units and intensive cardiac care units. Bhabha Atomic Research Centre has introduced respiration rate variability, cardiac output/ peripheral blood flow variability; integrated them with heart rate variability and study these changes in variety of diseases.

Peripheral Pulse Analyzer, a computer based System developed at Bhabha Atomic Research Centre, for the study of physiological variabilities has unique feature that it yields heart rate variability, respiration rate variability, cardiac output variability/ peripheral blood flow variability from a single data acquisition session from the patient. The picture shows Peripheral Pulse Analyzer system in operation developed at BARC. The data acquisition is controlled by the PC, serially connected to the acquisition unit. The variability analysis and transfer to database is performed by the PC with the help of Peripheral Pulse Analyzer package in post processing module.

FUNCTIONS

This System gives following facilities:

• Data Acquisition from all the devices developed at ED, BARC.
• Display of Acquired data in Time Domain, Frequency Domain and Non linear format like Poincare Plots.
• Deriving Different Variabilities from the Acquired Data.
• Saving of calculated parameters in Excel Database for further reporting and analysis.

SALIENT FEATURES

• User friendly.
• Easy & faster data entry and retrieval from Access/Excel Database.
• Easy adaptability by clinicians/ medical practitioners.
• Comparison facility of the data from the same disease group and with the normal group.
• Analysis of the data in the validation phase, user defined reports/queries for comparison of variability of different disease groups.
• Pictorial representation in the form of graph for comparing changes (increase/decrease) in the parameters (peak amplitude) for all variability and for all disease can be obtained to view the whole data at a glance.
• Queries are being used for finding out number of patients, average and standard deviation of a particular disease group.
• Till the frequency ranges are established for LF1, LF2, MF1, MF2, HF1 and HF2, flexibility to set the frequency ranges so that peak can be shifted automatically.
• Future expandability to accommodate new fields, variables, reports or queries.
• Future support for employing fuzzy logic or neural network approach to incorporate automatic machine generated report on the patient.

SPECIFICATIONS

Principle

• Short term analysis of variations in a physiological parameter as a function of time in time and frequency domain.

Parameters (Hardware dependent)

• Heart Rate, Respiration Rate, Stroke Volume, Cardiac Output, Peripheral Blood Flow(Left), Peripheral Blood Flow(Right), with Impedance Cardiovasograph
• Heart Rate, Peripheral Blood Flow with Oxygen Saturation Monitor
• Heart rate with ECG Machine

Method of Analysis

• Fast Fourier Transform

Output

• Option is available to record Six Parameters
• Six frequency range (user definable between 0.0 to 0.5 Hz.)
• Amplitude, Area, Skew ness, Centre Frequency, Lower Frequency Limit, Upper Frequency Limit of the peak automatically computed.
• Hardcopy purposes.
• Transfer of Data to database for further analysis.

Database

• Easy entry/ retrieval
• User defined reports/ queries
• Comparison between user defined graphs
• Pictorial representation of the results
• Future expandability
• Future support for using Fuzzy Logic for AI

Operating System

• Windows XX

Operating Environmental Conditions

• The instrument gives optimum performance with isolated earthing and at room temperature of around 27°C

PC Connectivity

• Standard A-type male to B-type male USB Cable

Electrode

• Silver plated copper band electrode

Output Connector

• 3-pin Metal round connector with 2 co-axial cables

Input Connector

• 3-pin Metal round connector with 2 co-axial cables

Power Supply

• 7-to-20V DC / 2A

APPLICATIONS

• Helpful in studying Physiological Variability.
• Helpful in Studying Autonomous Nervous System.
• Helpful in finding the effects of Allopathic/ Ayurvedic/ Homeopathic Medicines on the patients.

INFRASTRUCTURE

• Since this is electronic equipment it does not require large working space. 
  ~200 Square Feet area may be more than adequate
• Test Equipments 
  Test & measuring facility for electronic systems like 100 MHz Oscilloscope, Digital Voltmeter with 0.1 V resolution, PC with windows xx OS and required PCB designing software (optional)
• Other Facilities 
  Micro-controller Programming and Testing, Provision to import some components if not available locally (optional).

MANPOWER

• Man power: One experienced Electronics (Hardware & Software) Engineer, One Assistant & Two Technicians are required for production, testing, calibration of the instrument and Data collection.