The Microarrayer is a very precise computer controlled 3-axes robotics system to deposit high-density, gridded arrays of genomic DNA or similar biological materials at discrete locations in microscopic quantities. Such a capability permits for all possible genes that can be expressed in a given organism in a two-dimensional array at a high-density on a solid surface for high throughput analysis. These targets are then hybridized with fluorescence labeled complimentary sequences in a test sample (DNA or RNA). It is the first indigenously developed system in BARC and promises to make mutation detection, gene expression analysis and disease diagnosis in less time and is more efficient, thus revolutionizing in area of biotechnology and medicine.

FEATURES

• Servomotors & high resolution encoders for X , Y & Z axes
• Liquid handling by capillary action
• Micron level accuracy
• Contact printing
• Precise robotic system for automation
• Computer for control & data display
  

SOFTWARE FEATURES INCLUDE

• A Procedure creation wizard and automatic procedure validation
• Custom microarray designs
• Customizable Wash/Dry protocols
• Complete Sample tracking

APPLICATIONS

• Gene expression analysis in medicine and agriculture
• Disease diagnosis (Large scale genetic variation )
• High throughput mutation detection

The Microarrayer is a very precise computer controlled 3-axes robotics system to deposit high-density, gridded arrays of genomic DNA or similar biological materials at discrete locations in microscopic quantities. The robotic system based on servo motors with high-resolution encoders & advanced control scheme, well damped table and unique pin tip assembly to provide better positional accuracy of few micron, higher throughput and user friendly control software to define all critical parameters for printing operation. Both hardware and software are designed to provide high performance automation together with the flexibility required for individual sample handling and custom designed. The robot is designed to collect samples automatically from the wells of either a 96 or a 384-well micro-titre plate with up to 32 specially made pins by capillary action and deposits approximately 1 nano-litre on each slide.

FEATURES

• Servomotors, precise linear guides & high resolution encoders for X , Y & Z axes
• Micron level accuracy of biological sample spot
• Precise robotics system for automation
• Liquid handling by capillary action
• Vacuum chamber and cleaner for drying and cleaning of pins
• Hardware and software interlocks
• Computer for control & data display

SOFTWARE FEATURES INCLUDE

• A Procedure creation wizard and automatic procedure validation
• Custom microarray designs
• Customizable Wash/Dry protocols
• Complete Sample tracking

SPECIFICATIONS

APPLICATIONS

• Gene expression analysis
• Disease diagnosis (Large scale genetic variation )
• High throughput mutation detection

INFRASTRUCTUAL REQUIREMENT

a. Space

b. Manpower

• One Electronics or Electrical engineer for control system, hardware manufacturing, assembling, testing the system.
• One software engineer for software development, maintenance of control software of DNA Microarrayer system.

c. Power Supply

• Mains Voltage : 240 V
• Mains Fuse : 5 A
• Power Consumption : 300 W
• Operating Temperature : 0° C to 30° C
• Operating Humidity : 0 - 80% non-condensing

TEST EQUIPMENTS

• Standard test and measuring facility for instruments like Oscilloscope, DVM, Multimeter, Soldering machine, Co-ordinate measuring machine, Dial gauge etc.

OTHER FACILITIES

• Manufacturing facility with CNC machines