Aluminium (Al) is potentially neurotoxic due to its indiscriminate binding with various ligands (phosphate, citrate; proteins-transferrin, catecholamine). Al can cross blood brain barrier and accumulate in brain leading to memory impairment, cognitive dysfunction, neurodegenerative disorders (Parkinson's and Alzheimer's) etc. The toxic effect of Al is of concern in chronic renal failure patients on dialysis and patients receiving long term parenteral nutrition. Therefore, an accurate control of Al in commercial dialysis solutions is necessary (must be lower than 10 µg/L for dialysis fluids and 200 µg/L in drinking water) to determine its suitability. Aluminium Visual Detection Kit (AVDK) is useful for the detection of Al in peritoneal dialysis fluids and ground waters. Using this kit, the test samples can be immediately categorized as safe, permissible or toxic for their suitability with respect to aluminum.

1. Non-invasive test kit for on-site detection of Al down to 5 ppb in dialysis fluids and ground waters.
2. Low investment on infrastructure for preparing the kits.
3. Instantaneous results, Low cost and easy availability of the reagents.
4. With minimal instructions, kit can be used by any individual for qualitative and reproducible results.
5. Using this kit, the test samples can be immediately categorized as safe, permissible or toxic for their suitability with respect to aluminum.

Aluminium (Al) is potentially neurotoxic due to its indiscriminate binding with various ligands (phosphate, citrate; proteins-transferrin, catecholamine). Al can cross blood brain barrier and accumulate in brain leading to memory impairment, cognitive dysfunction, neurodegenerative disorders (Parkinson's and Alzheimer's) etc. The toxic effect of Al is of concern in chronic renal failure patients on dialysis and patients receiving long term parenteral nutrition. Therefore, an accurate control of Al in commercial dialysis solutions is necessary (must be lower than 10 µg/L for dialysis fluids and 200 µg/L in drinking water) to determine its suitability. A simple and rapid visual colorimetric method is therefore developed for the detection of Al in peritoneal dialysis fluids and ground waters. AVDK sensitivity is 0, 5, 10 and 20 µg/L (ppb).

1. Non-invasive test kit for on-site detection of Al down to 5 ppb in dialysis fluids and ground waters.
2. Low investment on infrastructure for preparing the kits.
3. Instantaneous results, Low cost and easy availability of the reagents.
4. With minimal instructions, kit can be used by any individual for qualitative and reproducible results.
5. Using this kit, the test samples can be immediately categorized as safe, permissible or toxic for their suitability with respect to aluminum.

An Aluminium Visual Detection Kit (AVDK) consists of:

1. 1 easy-to-read colour chart
2. 1 micropipette
3. 2 Nos 100 mL volumetric flasks (Glass)
4. Reagent 1
5. Reagent 2
6. Reagent 3

Infrastructure Requirements

1. A laboratory room (3m X 3m) with the following equipment:
1. 5 Standard flasks (100 mL) and balance (1 mg precision)

Statutory Requirements

1. Statutory clearances for safe handling of various acids, chemicals and a small scale industrial registration are required.

Raw Materials

1. All the raw materials required for making the Aluminium detection kits are easily available in the local market.

Manpower Requirements

1. One technician for preparing the reagents and one chemist for carrying out the reagent quality assessment by checking with standards are required.